Prohibitin 2 (PHB2) Peptide
PHB2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Prohibitin 2 (PHB2) products
- Prohibitin 2 (PHB2)
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PHB2 antibody (Catalog #: ARP48316_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Prohibitin 2 (PHB2)
- 背景
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PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Protein Interaction Partner: ESR1,PTMA,AKT1,ESR1,HDAC1,HDAC2,HDAC3,HDAC5,MEF2A,MYOD1,PTMA,UPF2,CDC25B,COPG,CTNNB1,DDX20,EPPK1,ESR1,JUP,LGALS3BP,MMS19,NUP205,NUP93,PDXDC1,PTMA,RIPK2,RUNX3,SERINC3,SIRT2,TFE3,TH1L,TIMM50,USP15
Protein Size: 299 - 分子量
- 33 kDa
- 基因ID
- 11331
- NCBI登录号
- NM_007273, NP_009204
- UniProt
- Q99623
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