Peroxisomal Biogenesis Factor 5 (PEX5) (N-Term) Peptide
PEX5
适用: 人
宿主: 合成
BP, WB
Quick Overview for Peroxisomal Biogenesis Factor 5 (PEX5) (N-Term) Peptide (ABIN981604)
抗原
PEX5
(Peroxisomal Biogenesis Factor 5 (PEX5))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PEX5 antibody (Catalog #: ARP56101_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
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背景
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PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD).
Alias Symbols: PTS1R, PXR1, PTS1-BP
Protein Interaction Partner: PEX12,PEX14,AGXT,ATM,DDO,HSPA1A,PDZK1,PEX10,PEX12,PEX13,PEX14,PEX7,SCARB1,SIRT3,SNUPN,SSTR5,ATM,CAT,DDO,PDZK1,PEX10,PEX12,PEX13,PEX14,PEX7,SIRT3,SNUPN
Protein Size: 631 -
分子量
- 70 kDa
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基因ID
- 5830
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NCBI登录号
- NM_000319, NP_000310
抗原
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