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Peroxisomal Biogenesis Factor 19 (PEX19) (C-Term) Peptide

PEX19 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981599
发货至: 中国
  • 抗原 See all PEX19 products
    PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
    蛋白结构域
    C-Term
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PEX19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
    别名
    BEST:GH03076 Peptide, CG5325 Peptide, DmelPex19 Peptide, Dmel\\CG5325 Peptide, D1S2223E Peptide, HK33 Peptide, PBD12A Peptide, PMP1 Peptide, PMPI Peptide, PXF Peptide, PXMP1 Peptide, Pxf Peptide, PxF Peptide, Peroxin-19 Peptide, Peroxin 19 Peptide, Peroxisomal farnesylated protein Peptide, peroxisomal biogenesis factor 19 Peptide, Pex19 Peptide, Bm1_19905 Peptide, PEX19 Peptide
    背景
    This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

    Alias Symbols: D1S2223E, FLJ55296, HK33, PMP1, PMPI, PXF, PXMP1

    Protein Interaction Partner: ABCD1,ABCD2,ABCD3,PEX10,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,ABCD1,ABCD2,ABCD3,CDKN2A,PEX10,PEX11A,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,PMP22,PXMP4,SLC25A17,SLC34A1,SMAD2,ABCD1,ABCD2,ABCD3,PEX10,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,SLC25A17

    Protein Size: 299
    分子量
    33 kDa
    基因ID
    5824
    NCBI登录号
    NM_002857, NP_002848
    UniProt
    P40855
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