phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (C-Term) Peptide
PDE6B
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN981514
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (C-Term) Peptide (ABIN981514)
抗原
PDE6B
(phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- RQHEHVIHLM DIAIIATDLA LYFKKRAMFQ KIVDESKNYQ DKKSWVEYLS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PDE6B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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背景
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Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CSNB3, CSNBAD2, PDEB, RP40, rd1
Protein Size: 575 -
分子量
- 63 kDa
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基因ID
- 5158
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NCBI登录号
- NM_001145292, NP_001138764
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UniProt
- E7ETT3
抗原
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