phosphodiesterase 4B, cAMP-Specific (PDE4B) (Middle Region) Peptide
PDE4B
适用: 人
宿主: 合成
BP, WB
Quick Overview for phosphodiesterase 4B, cAMP-Specific (PDE4B) (Middle Region) Peptide (ABIN981510)
抗原
PDE4B
(phosphodiesterase 4B, cAMP-Specific (PDE4B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PDE4B antibody (Catalog #: ARP56256_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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phosphodiesterase 4B, cAMP-Specific (PDE4B) peptide
PDE4B 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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背景
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The specific function of this protein remains unknown.This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB
Protein Interaction Partner: PRKACA
Protein Size: 564 -
分子量
- 64 kDa
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基因ID
- 5142
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NCBI登录号
- NM_001037339, NP_001032416
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UniProt
- Q5TEK5
抗原
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