Proliferating Cell Nuclear Antigen (PCNA) Peptide
PCNA
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all PCNA products
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PCNA antibody (Catalog #: AVARP03018_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
- 背景
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PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Alias Symbols: MGC8367
Protein Interaction Partner: APEX2,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,CDKN1A,DDX17,DNMT1,DSCC1,EXO1,FEN1,FEN1,FEN1,GADD45A,GADD45A,GADD45A,GADD45A,GADD45B,GADD45B,GADD45G,LIG1,MSH3,MSH6,MUTYH,MYBBP1A,NONO,PCNA,POLB,POLD1,POLD2,POLD3,POLDIP2,POLE,PRKDC,RFC2,RFC3,RFC5,TCOF1,UNG,BAZ1B,KCTD13,APEX1,APEX2,BAZ1B,CCNB1,CCND1,CCND3,CCNO,CDC25C,CDC6,CDK1,CDK2,CDK5,CDK6,CDKN1A,CDKN1C,CDT1,CHAF1A,CHTF18,CHTF8,DHX9,DNMT1,DNTT,DNTTIP2,DSCC1,EP300,ERCC5,FEN1,GADD45A,GADD45B,GADD45G,HDAC1,HUS1,ING1,KCTD13,LIG1,MCL1,MSH2,MSH3,MSH6,MUTYH,MYBBP1A,PARP1,PCNA,POLB,POLD1,POLD2,POLD3,POLD4,POLDIP2,POLE,POLH,POLI,POLL,POLM,PPP1CA,PRKDC,PTMA,RAD9A,RBBP8,RFC1,RFC2,RFC3,RFC4,RFC5,RPA1,SEC23IP,SUB1,TCOF1,UBB,UNG,WRN,XRCC1,XRCC5,XRCC6,YBX1,AIRE,ANXA2,APEX1,APEX2,CCNA2,CCND1,CCND3,CCNO,CDC25C,CDC6,CDK2,CDK4,CDKN1A,CDKN1C,CDT1,CHAF1A,CHTF18,CLSPN,CUL4A,DDB1,DNMT1,DNTT,EP300,ERCC5,FEN1,GADD45A,GADD45G,Gadd45b,HDAC1,HLTF,HUS1,ING1,KCTD13,KIAA0101,LIG1,MCL1,MSH2,MSH3,MSH6,MUTYH,MYBBP1A,OTUB1,PARP1,PCNA,PMS2,POLD1,POLD2,POLD3,POLDIP2,POLE,POLH,POLL,PRKDC,Polk,RFC1,RFC2,RFC3,RFC4,RFC5,RPA1,RUVBL2,SMARCA4,TIMELESS,UBC,WRN,XRCC1,XRCC5,XRCC6,YBX1
Protein Size: 261 - 分子量
- 29 kDa
- 基因ID
- 5111
- NCBI登录号
- NM_002592, NP_002583
- UniProt
- P12004
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