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Protocadherin alpha 3 (PCDHA3) (N-Term) Peptide

PCDHA3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981449
发货至: 中国
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Quick Overview for Protocadherin alpha 3 (PCDHA3) (N-Term) Peptide (ABIN981449)

抗原

PCDHA3 (Protocadherin alpha 3 (PCDHA3))

宿主

资源

  • 2
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    产品特性

    This is a synthetic peptide designed for use in combination with anti-PCDHA3 antibody (Catalog #: ARP50006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    PCDHA3 (Protocadherin alpha 3 (PCDHA3))

    背景

    PCDHA3 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

    Alias Symbols: MGC141669, PCDH-ALPHA3

    Protein Size: 950

    分子量

    99 kDa

    基因ID

    56145

    NCBI登录号

    NM_018906, NP_061729

    UniProt

    Q9Y5H8
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