Pyruvate Carboxylase (PC) (C-Term) Peptide
PC
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN981417
发货至:
中国
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Contact Info
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中国
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Quick Overview for Pyruvate Carboxylase (PC) (C-Term) Peptide (ABIN981417)
抗原
PC
(Pyruvate Carboxylase (PC))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- SLPPLDLQAL EKELVDRHGE EVTPEDVLSA AMYPDVFAHF KDFTATFGPL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PC Antibody(ARP59606_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PC (Pyruvate Carboxylase (PC))
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背景
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This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Alias Symbols: PCB
Protein Interaction Partner: GOT2,MDH2,GOT1,MDH2
Protein Size: 1178 -
分子量
- 127 kDa
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基因ID
- 5091
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NCBI登录号
- NM_001040716, NP_001035806
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UniProt
- P11498
抗原
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