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Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) Peptide

PARP16 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981362
发货至: 中国
  • 抗原 See all PARP16 products
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PARP16 antibody (Catalog #: ARP33751_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    别名
    PARP16 Peptide, zgc:77744 Peptide, ARTD15 Peptide, C15orf30 Peptide, pART15 Peptide, BC055447 Peptide, C79952 Peptide, PARP-16 Peptide, LRRGT00109 Peptide, RGD1306243 Peptide, poly(ADP-ribose) polymerase family member 16 Peptide, poly(ADP-ribose) polymerase family member 16 L homeolog Peptide, poly (ADP-ribose) polymerase family, member 16 Peptide, PARP16 Peptide, parp16.L Peptide, parp16 Peptide, Parp16 Peptide
    背景
    Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

    Alias Symbols: pART15, C15orf30

    Protein Size: 323
    分子量
    36 kDa
    基因ID
    54956
    NCBI登录号
    NM_017851, NP_060321
    UniProt
    Q6PK64
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