Poly (ADP-Ribose) Polymerase 1 (PARP1) Peptide
PARP1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all PARP1 products
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PARP1 antibody (Catalog #: ARP33754_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 662-1014) peptide
PARP1 适用: 人 宿主: 大肠杆菌（E. Coli） SDS Dithiothreitol (DTT)
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- 背景
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PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Alias Symbols: C12orf6, PARP1
Protein Interaction Partner: GTPBP3,DCAF11,GTPBP3,LYZ,NUP98,OTUD4,RNF114
Protein Size: 1014 - 分子量
- 113 kDa
- 基因ID
- 57097
- NCBI登录号
- NM_001618, NP_001609
- UniProt
- P09874
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