Proliferation-Associated 2G4, 38kDa (PA2G4) Peptide
PA2G4
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN981291
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Proliferation-Associated 2G4, 38kDa (PA2G4) Peptide (ABIN981291)
抗原
PA2G4
(Proliferation-Associated 2G4, 38kDa (PA2G4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PA2G4 antibody (Catalog #: ARP47601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
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背景
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PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EBP1, HG4-1, p38-2G4
Protein Interaction Partner: ERBB3,HDAC2,AR,ERBB3,EXOSC5,HDAC2,PRKCA,PRKCB,PRKCG,RB1,SIN3A,SUMO4,AR,ATR,ERBB3,HDAC2,MTOR,RB1,SGK1,USP39
Protein Size: 394 -
分子量
- 44 kDa
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基因ID
- 5036
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NCBI登录号
- NM_006191, NP_006182
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UniProt
- Q9UQ80
抗原
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