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Oncostatin M Receptor (OSMR) (Middle Region) Peptide

OSMR 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981219
发货至: 中国
  • 抗原 See all Oncostatin M Receptor (OSMR) products
    Oncostatin M Receptor (OSMR)
    蛋白结构域
    Middle Region
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-OSMR antibody (Catalog #: ARP46396_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Oncostatin M Receptor (OSMR)
    别名
    OSMRB Peptide, PLCA1 Peptide, oncostatin M receptor Peptide, OSMR Peptide, Osmr Peptide
    背景
    Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1

    Protein Interaction Partner: IL6ST,JAK1,JAK2,OSM,ERBB2,IL6ST

    Protein Size: 979
    分子量
    110 kDa
    基因ID
    9180
    NCBI登录号
    NM_003999, NP_003990
    UniProt
    Q99650
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