Origin Recognition Complex, Subunit 3 (ORC3) (N-Term) Peptide
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Quick Overview for Origin Recognition Complex, Subunit 3 (ORC3) (N-Term) Peptide (ABIN981200)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- RFETYQLIWQ QMKSENERLQ EELNKNLFDN LIEFLQKSHS GFQKNSRDLG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ORC3L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
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背景
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The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: CCNE2,CDC45,CDC6,CDK4,DBF4,MCM10,MCM5,MCM7,ORC1,ORC2,ORC3,ORC4,ORC5,ORC6,BRCA1,MCM4,MCM7,ORC2,ORC4,ORC5,ORC6,TERF2
Protein Size: 712 -
分子量
- 82 kDa
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基因ID
- 23595
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NCBI登录号
- NM_181837, NP_862820
抗原
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