Optic Atrophy 1 (Autosomal Dominant) (OPA1) (N-Term) Peptide
OPA1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN981141
发货至:
中国
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Contact Info
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Quick Overview for Optic Atrophy 1 (Autosomal Dominant) (OPA1) (N-Term) Peptide (ABIN981141)
抗原
OPA1
(Optic Atrophy 1 (Autosomal Dominant) (OPA1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-OPA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
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背景
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This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Protein Size: 924 -
分子量
- 102 kDa
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基因ID
- 4976
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NCBI登录号
- NM_130831, NP_570844
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UniProt
- E5KLK2
抗原
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