2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (N-Term) Peptide
OAS2
适用: 人
宿主: 合成
BP, WB
Quick Overview for 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (N-Term) Peptide (ABIN981073)
抗原
OAS2
(2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-OAS2 antibody (Catalog #: ARP40851_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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背景
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OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC78578
Protein Size: 687 -
分子量
- 79 kDa
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基因ID
- 4939
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NCBI登录号
- NM_002535, NP_002526
抗原
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