Neuronal Cell Adhesion Molecule (NRCAM) Peptide
NRCAM
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN980952
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Neuronal Cell Adhesion Molecule (NRCAM) Peptide (ABIN980952)
抗原
NrCAM (NRCAM)
(Neuronal Cell Adhesion Molecule (NRCAM))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NRCAM antibody (Catalog #: ARP44833_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Neuronal Cell Adhesion Molecule (NRCAM) peptide
NRCAM 宿主: 合成 BP, WB, IHC
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
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背景
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Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA0343, MGC138845, MGC138846
Protein Interaction Partner: ANK2,CNTN2,MACF1,MAGI3,NFASC,NRCAM,PTPRB,CNTN2,PTPRB
Protein Size: 1304 -
分子量
- 141 kDa
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基因ID
- 4897
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NCBI登录号
- NM_001037132, NP_001032209
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UniProt
- Q92823
抗原
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