GTPase NRas (NRAS) (Middle Region) Peptide
NRAS
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all GTPase NRas (NRAS) products
- GTPase NRas (NRAS)
- 蛋白结构域
- Middle Region
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-NRAS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- GTPase NRas (NRAS)
- 别名
- NRAS Peptide, AV095280 Peptide, N-ras Peptide, ALPS4 Peptide, NRAS1 Peptide, NS6 Peptide, N-RAS Peptide, fj99a10 Peptide, wu:fj99a10 Peptide, zgc:100761 Peptide, zras-b1 Peptide, H-RAS Peptide, HRAS Peptide, GTPase NRas Peptide, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog Peptide, NRAS proto-oncogene, GTPase Peptide, neuroblastoma ras oncogene Peptide, neuroblastoma RAS viral oncogene homolog Peptide, Tsp_01117 Peptide, nras.L Peptide, Nras Peptide, NRAS Peptide, nras Peptide
- 背景
-
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Alias Symbols: ALPS4, N-ras, NRAS1, NS6
Protein Interaction Partner: RAF1,ACVR1,ARHGAP4,BCL2,PIK3CA,PLCE1,RACGAP1,RAF1,RAP1GDS1,RASGRP2,RASSF5,SHOC2,SMAD4,SMURF2,MLLT4,PIK3CG,PLCE1,RAF1,RAP1GDS1
Protein Size: 189 - 分子量
- 21 kDa
- 基因ID
- 4893
- NCBI登录号
- NM_002524, NP_002515
- UniProt
- P01111
-
You are here:
