Neuronal Pentraxin II (NPTX2) (N-Term) Peptide
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Quick Overview for Neuronal Pentraxin II (NPTX2) (N-Term) Peptide (ABIN980857)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- VQQKETLGAQ REAIRELTGK LARCEGLAGG KARGAGATGK DTMGDLPRDP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NPTX2 Antibody(ARP56365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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背景
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NARP, NP-II, NP2
Protein Interaction Partner: NPTXR,Nptx1,Nptxr
Protein Size: 431 -
分子量
- 47 kDa
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基因ID
- 4885
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NCBI登录号
- NM_002523, NP_002514
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UniProt
- P47972
抗原
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