NK2 Homeobox 5 (NKX2-5) (N-Term) Peptide
NKX2-5
适用: 人, 小鼠
宿主: 合成
BP, WB
产品编号 ABIN980742
发货至:
中国
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Contact Info
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Quick Overview for NK2 Homeobox 5 (NKX2-5) (N-Term) Peptide (ABIN980742)
抗原
NK2 Homeobox 5 (NKX2-5)
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Nkx2-5 antibody (Catalog #: ARP36946_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NK2 Homeobox 5 (NKX2-5)
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背景
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Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.
Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman
Protein Interaction Partner: Foxh1,Mef2c,Smarca4,SRF,SRF
Protein Size: 318 -
分子量
- 34 kDa
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基因ID
- 18091
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NCBI登录号
- NM_008700, NP_032726
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UniProt
- P42582
抗原
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