Nuclear Factor, Interleukin 3 Regulated (NFIL3) Peptide
NFIL3
适用: 人
宿主: 合成
BP, WB
Quick Overview for Nuclear Factor, Interleukin 3 Regulated (NFIL3) Peptide (ABIN980664)
抗原
NFIL3
(Nuclear Factor, Interleukin 3 Regulated (NFIL3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NFIL3 antibody (Catalog #: ARP31177_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Nuclear Factor, Interleukin 3 Regulated (NFIL3) peptide
NFIL3 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
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背景
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NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
Protein Interaction Partner: CREB3,DR1,NFIL3,DR1
Protein Size: 462 -
分子量
- 51 kDa
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基因ID
- 4783
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NCBI登录号
- NM_005384, NP_005375
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UniProt
- Q16649
抗原
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