Neurofibromin 2 (NF2) (C-Term) Peptide
NF2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Neurofibromin 2 (NF2) (C-Term) Peptide (ABIN980635)
抗原
Merlin (NF2)
(Neurofibromin 2 (NF2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- MAEESERRAK EADQLKQDLQ EAREAERRAK QKLLEIATKP TYPPMNPIPA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Merlin (NF2) (Neurofibromin 2 (NF2))
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背景
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This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Alias Symbols: ACN, BANF, SCH
Protein Interaction Partner: EZR,HGS,NF2,PAK1,SDCBP,SLC9A3R1,TARBP2,TSC1,CD44,CTNNB1,ERBB2,EZR,HGS,ITGB1,NF2,PAK1,PXN,RALGDS,SCHIP1,SDCBP,SGSM3,SLC9A3R1,SPTBN1,TARBP2,TSC1,XPO1,AGAP2,AKT1,AMOT,ARHGAP32,CD44,CUL4A,DDB1,EZR,HGS,MED28,NF2,PXN,PYGO2,RIT1,SCHIP1,SDCBP,SGSM3,SLC9A3R1,SOS1,
Protein Size: 507 -
分子量
- 56 kDa
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基因ID
- 4771
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NCBI登录号
- NM_181830, NP_861968
抗原
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