Neuralized Homolog 2 (NEURL2) Peptide
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Quick Overview for Neuralized Homolog 2 (NEURL2) Peptide (ABIN980619)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NEURL2 antibody (Catalog #: ARP52524_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NEURL2 (Neuralized Homolog 2 (NEURL2))
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背景
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NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Alias Symbols: C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3
Protein Interaction Partner: CTNNB1
Protein Size: 285 -
分子量
- 32 kDa
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基因ID
- 140825
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NCBI登录号
- NM_080749, NP_542787
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UniProt
- Q9BR09
抗原
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