MAX Interactor 1 (MXI1) Peptide
MXI1
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all MXI1 products
- MXI1 (MAX Interactor 1 (MXI1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MXI1 antibody (Catalog #: ARP31403_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MXI1 (MAX Interactor 1 (MXI1))
- 别名
- mxi Peptide, mad2 Peptide, mxd2 Peptide, xmxi1 Peptide, MGC89544 Peptide, MXI1 Peptide, etID309773.22 Peptide, fb16b12 Peptide, fb55f03 Peptide, wu:fb16b12 Peptide, wu:fb55f03 Peptide, wu:fd06a08 Peptide, wu:fz74f10 Peptide, ENSMUSG00000067085 Peptide, Gm10197 Peptide, Mad2 Peptide, bHLHc11 Peptide, MXI-WR Peptide, MAD2 Peptide, MXD2 Peptide, MXI Peptide, MAX interactor 1, dimerization protein Peptide, max interactor 1, dimerization protein Peptide, MAX interactor 1, dimerization protein L homeolog Peptide, mxi1 Peptide, MXI1 Peptide, Mxi1 Peptide, mxi1.L Peptide
- 背景
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Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Alias Symbols: MAD2, MGC43220, MXD2, MXI, bHLHc11
Protein Interaction Partner: MAX,MYC,SIN3A,SIN3B,SMC3,MAX,SMC3
Protein Size: 295 - 分子量
- 26 kDa
- 基因ID
- 4601
- NCBI登录号
- NM_130439, NP_569157
- UniProt
- P50539
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