5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (N-Term) Peptide
MTRR
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MTRR products
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- YDLKTETAPL VVVVSTTGTG DPPDTARKFV KEIQNQTLPV DFFAHLRYGL
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MTRR Antibody(ARP57657_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
- 背景
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Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: MGC129643, MSR, cblE
Protein Interaction Partner: MMAB
Protein Size: 725 - 分子量
- 80 kDa
- 基因ID
- 4552
- NCBI登录号
- NM_024010, NP_076915
- UniProt
- Q9UBK8
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