Mitochondrial Ribosomal Protein L49 (MRPL49) (N-Term) Peptide
MRPL49
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MRPL49 products
- MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- IMVTFRNQAS RPYSFYSSLI SYEEDQRQGA EPRKNFVKPN ETKTYFWKVQ
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MRPL49 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))
- 背景
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This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Alias Symbols: C11orf4, L49mt, MGC10656, NOF, NOF1, MRP-L49
Protein Interaction Partner: ASGR2,CALR,CANX,F10,F2,F9,HSPA5,LMAN1,LRP1,MCFD2,PHYH,PROC,PROS1,VWF,CANX,F10,LMAN1,LRP1,PHYH,PROS1,VWF
Protein Size: 2351 - 分子量
- 79 kDa
- 基因ID
- 740
- NCBI登录号
- NM_004927, NP_004918
- UniProt
- Q13405
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