MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (N-Term) Peptide
MRE11A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN980225
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (N-Term) Peptide (ABIN980225)
抗原
Mre11 (MRE11A)
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- N-Term
-
序列
- DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-MRE11A Antibody(ARP56644_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
-
背景
-
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: ATLD, HNGS1, MRE11, MRE11B
Protein Interaction Partner: NBN,NEK1,RAD50,ATM,CCNE1,DCLRE1C,EP300,FANCD2,H2AFX,LIG1,NBN,NEK1,RAD50,XRCC6,ATM,ATM,ATR,BLM,BRCA1,LIG1,MDC1,MLH1,MSH2,MSH6,NBN,NBN,PRKDC,RAD50,RECQL5,RFC1,TERF2,TERF2IP,TP53,USP11,XRCC6
Protein Size: 708 -
分子量
- 80 kDa
-
基因ID
- 4361
-
NCBI登录号
- NM_005591, NP_005582
-
UniProt
- P49959
抗原
-
You are here:
