Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Peptide
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Quick Overview for Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Peptide (ABIN980146)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MMP1 antibody (Catalog #: ARP42039_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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背景
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Alias Symbols: CLG, CLGN
Protein Interaction Partner: F2R,ACAN,BCAN,BSG,CCL13,CCL2,CCL7,CD44,CMA1,COL2A1,IGFBP3,ITGA2,MMP7,SERPINA3,TFPI,TIMP1,TNFSF11,BCAN,BSG,ITGA2,TIMP1
Protein Size: 469 -
分子量
- 52 kDa
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基因ID
- 4312
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NCBI登录号
- NM_002421, NP_002412
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UniProt
- P03956
抗原
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