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Melanophilin (MLPH) (C-Term) Peptide

MLPH 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN980129
发货至: 中国
  • 抗原 See all Melanophilin (MLPH) products
    Melanophilin (MLPH)
    蛋白结构域
    C-Term
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    NLPIFLPRVA GKLGKRPEDP NADPSSEAKA MAVPYLLRRK FSNSLKSQGK
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MLPH Antibody(ARP59494_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Melanophilin (MLPH)
    背景
    This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

    Alias Symbols: MGC2771, MGC59733, SLAC2-A

    Protein Interaction Partner: MYO5A,RAB27A,RAB27B,ACTA1,MYO5A,RAB10,RAB27A,RAB27B,RPH3A

    Protein Size: 600
    分子量
    66 kDa
    基因ID
    79083
    NCBI登录号
    NM_024101, NP_077006
    UniProt
    Q9BV36
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