Mediator Complex Subunit 21 (MED21) Peptide
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Quick Overview for Mediator Complex Subunit 21 (MED21) Peptide (ABIN979945)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MED21 antibody (Catalog #: ARP37735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MED21 (Mediator Complex Subunit 21 (MED21))
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背景
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MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: CDKN1A,TFF1,THRA,THRB,BRCA1,BTF3,CDK8,CDK9,POLR2A,TCEB3,TFG,THRA,THRB,BRCA1,CDK7,CDK8,CREBBP,ESR1,ESR2,GTF2B,GTF2E1,GTF2F1,GTF2H4,HNF4A,KAT2B,MED1,MED10,MED14,MED18,MED19,MED26,MED28,MED29,MED30,MED6,MED9,POLR2A,PPARGC1A,SMARCB1,TCERG1,THRA,VDR
Protein Size: 144 -
分子量
- 15 kDa
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基因ID
- 9412
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NCBI登录号
- NM_004264, NP_004255
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UniProt
- Q13503
抗原
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