This is a synthetic peptide designed for use in combination with anti-MED21 antibody (Catalog #: ARP37735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: CDKN1A,TFF1,THRA,THRB,BRCA1,BTF3,CDK8,CDK9,POLR2A,TCEB3,TFG,THRA,THRB,BRCA1,CDK7,CDK8,CREBBP,ESR1,ESR2,GTF2B,GTF2E1,GTF2F1,GTF2H4,HNF4A,KAT2B,MED1,MED10,MED14,MED18,MED19,MED26,MED28,MED29,MED30,MED6,MED9,POLR2A,PPARGC1A,SMARCB1,TCERG1,THRA,VDR