Minichromosome Maintenance Deficient 4 (MCM4) Peptide
MCM4
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN979897
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Minichromosome Maintenance Deficient 4 (MCM4) Peptide (ABIN979897)
抗原
MCM4
(Minichromosome Maintenance Deficient 4 (MCM4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-MCM4 antibody (Catalog #: ARP36649_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
-
背景
-
The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. The MCM4 gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks.
Alias Symbols: CDC21, CDC54, hCdc21, P1-CDC21
Protein Interaction Partner: MCM6,MCM7,MCM4,MCM6,MCM7,CCNA1,CDC5L,CDC7,CDK1,CDK2,MCM10,MCM2,MCM3,MCM4,MCM6,MCM7,MCM8,ORC2L,ORC6L,SSRP1,SUPT16H,CDC7,CDK2,CDT1,DBF4,ING5,MCM2,MCM4,MCM5,MCM6,MCM7,MCM8,ORC1L,ORC2L,ORC3L,ORC4L,ORC5L,ORC6L,RPA1,RPA2,USP7
Protein Size: 863 -
分子量
- 95 kDa
-
基因ID
- 4173
-
NCBI登录号
- NM_005914, NP_005905
-
UniProt
- P33991
抗原
-
You are here:
