Minichromosome Maintenance Complex Component 3 (MCM3) Peptide
MCM3
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN979895
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Minichromosome Maintenance Complex Component 3 (MCM3) Peptide (ABIN979895)
抗原
MCM3
(Minichromosome Maintenance Complex Component 3 (MCM3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-MCM3 antibody (Catalog #: ARP36645_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
-
背景
-
MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Alias Symbols: HCC5, MGC1157, P1-MCM3, P1.h, RLFB
Protein Interaction Partner: MCM2,MCM2,MCM5,MCM5,MCM7,MCM7,CDC45,CDC5L,CDC6,CDC7,CDK2,DBF4,HAUS1,MCM10,MCM2,MCM3AP,MCM4,MCM5,MCM6,MCM7,ORC2L,ORC4L,ORC5L,PLK1,POLR2A,PPP2R1A,PPP2R1B,RAD52,STAT1,SUPT16H,CDC45,CDC6,CDC7,DBF4,ENSA,MCM2,MCM3AP,MCM5,MCM7,ORC2L,ORC4L,ORC5L,PAK2,PMS2,PNKP,PTP4A3,RPA2,SNCG,WDR8
Protein Size: 808 -
分子量
- 89 kDa
-
基因ID
- 4172
-
NCBI登录号
- NM_002388, NP_002379
-
UniProt
- P25205
抗原
-
You are here:
