Microtubule-Associated Protein tau (MAPT) Peptide
MAPT
适用: 人
宿主: 合成
BP, WB, IHC
Quick Overview for Microtubule-Associated Protein tau (MAPT) Peptide (ABIN979811)
抗原
MAPT
(Microtubule-Associated Protein tau (MAPT))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MAPT antibody (Catalog #: ARP48103_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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背景
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MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Protein Interaction Partner: YWHAZ,GSK3B,AATF,ABL1,ACTB,APOE,CALM1,CAMK2A,CASP1,CASP3,CASP6,CASP7,CASP8,CDK1,CDK5,CDK5,CDK5,FLJ10357,FYN,GSK3A,GSK3B,HSPA8,MAPK12,MAPT,MARK1,MARK4,OGT,PHKG1,PIN1,PKN1,PPP2CA,PPP2CB,PPP2R5A,PPP5C,PRKCD,PSEN1,RPS6KA3,RPS6KB1,S100B,SNCA,SPTB,STAU1,STUB1,STXBP1,TUBA4A,TUBB,UBB,USP9Y,YWHAB,YWHAZ,AATF,APOE,BAG1,CALM1,FYN,HSPA8,MARK4,PARK2,PIN1,PSEN1,S100B,SNCA,STUB1,STXBP1,UBC,YWHAB,YWHAB,YWHAZ
Protein Size: 441 -
分子量
- 46 kDa
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基因ID
- 4137
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NCBI登录号
- NM_005910, NP_005901
抗原
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