V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide
MAF
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN979702
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide (ABIN979702)
抗原
MAF
(V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalog #: ARP38607_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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背景
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: CREBBP,EP300,CREBBP,EP300,ETS1,FOS,JUN,MAF,MAFA,MAFG,MYB,SMARCA5,SOX9,USF2,CREBBP,EP300,ETS1,HOXD12,MAF,MAFG,MYB,SOX9,USF2
Protein Size: 373 -
分子量
- 38 kDa
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基因ID
- 4094
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NCBI登录号
- NM_001031804, NP_001026974
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UniProt
- O75444
抗原
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