Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptide
LTB
适用: 人
宿主: 合成
BP, WB
Quick Overview for Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptide (ABIN979642)
抗原
LTB
(Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-LTB Antibody(ARP45280_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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背景
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: LTA,LTB,LTBR,TNFRSF1A,TNFSF14,LTA,TNFRSF1A
Protein Size: 244 -
分子量
- 25 kDa
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基因ID
- 4050
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NCBI登录号
- NM_002341, NP_002332
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UniProt
- Q06643
抗原
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