Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide
LRRC8A
适用: 人
宿主: 合成
BP, WB
Quick Overview for Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide (ABIN979603)
抗原
LRRC8A
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-LRRC8A antibody (Catalog #: ARP49452_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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背景
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LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Alias Symbols: FLJ10337, KIAA1437, LRRC8, AGM5
Protein Size: 810 -
分子量
- 94 kDa
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基因ID
- 56262
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NCBI登录号
- NM_019594, NP_062540
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UniProt
- Q8IWT6
抗原
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