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Lipopolysaccharide Binding Protein (LBP) Peptide

LBP 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN979220
发货至: 中国
  • 抗原 See all LBP products
    LBP (Lipopolysaccharide Binding Protein (LBP))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-LBP antibody (Catalog #: ARP41546_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    LBP (Lipopolysaccharide Binding Protein (LBP))
    别名
    BPIFD2 Peptide, Bpifd2 Peptide, Ly88 Peptide, LPSBP Peptide, LBP Peptide, lipopolysaccharide binding protein Peptide, lipopolysaccharide-binding protein Peptide, LBP Peptide, Lbp Peptide, LOC100472839 Peptide
    背景
    LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.

    Alias Symbols: MGC22233, BPIFD2

    Protein Interaction Partner: APOA1,CAMP,CD14,CFHR1,RPS21,APOA1,CD14,CFHR1,IRF6

    Protein Size: 481
    分子量
    51 kDa
    基因ID
    3929
    NCBI登录号
    NM_004139, NP_004130
    UniProt
    P18428
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