Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-KRT18 antibody (Catalog #: ARP40206_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
Cytokeratin 18 (KRT18)
(Keratin 18 (KRT18))
背景
KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: K18, CYK18
Protein Interaction Partner: CBL,TRADD,CAMK2A,CASP3,CASP6,CASP7,CASP8,CBL,CCDC85B,CDK1,COL17A1,DEDD,DNAJB6,EGFR,EXOC8,HGS,HSPA1A,HSPA5,KRT15,KRT5,KRT8,LDOC1,MAPK14,NME7,PKD1,PKP2,PNN,PRKCA,PRKCE,RAF1,RHPN2,RPS6KA3,SERPINE1,SHC1,TCHP,TNFRSF1B,TRADD,TUBG1,TUBGCP4,USH2A,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ALK,CBL,CCDC85B,CLEC3B,COL17A1,DEDD,DNAJB6,EXOC8,GRB2,HGS,HSPA4,KRT15,KRT5,KRT72,KRT8,LDOC1,MCC,NME7,PKD1,PKP2,PKP3,PKP3,PNN,PPM1B,PRKCE,TNFRSF1B,TRADD,TUBGCP4,USP32,YWHAQ