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Karyopherin alpha 6 (Importin alpha 7) (KPNA6) Peptide

KPNA6 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN979104
发货至: 中国
  • 抗原 See all KPNA6 products
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-KPNA6 antibody (Catalog #: ARP54879_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    别名
    IPOA7 Peptide, Kpna5 Peptide, NPI-2 Peptide, KPNA7 Peptide, karyopherin subunit alpha 6 Peptide, karyopherin (importin) alpha 6 Peptide, karyopherin alpha 6 (importin alpha 7) Peptide, karyopherin alpha 6 (importin alpha 7) S homeolog Peptide, KPNA6 Peptide, Kpna6 Peptide, kpna6.S Peptide
    背景
    The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KPNA6 is a member of the importin alpha family.Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FLJ11249, IPOA7, KPNA7, MGC17918

    Protein Interaction Partner: ANP32A,BRCA1,CSE1L,KPNB1,RELB,STAT1,STAT3,TAF9,KPNB1,MEPCE,RELB,SPOP

    Protein Size: 536
    分子量
    60 kDa
    基因ID
    23633
    NCBI登录号
    NM_012316, NP_036448
    UniProt
    O60684
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