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Klotho (KL) (N-Term) Peptide

KL 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN978987
发货至: 中国
  • 抗原 See all Klotho (KL) products
    Klotho (KL)
    蛋白结构域
    N-Term
    宿主
    小鼠
    资源
    • 12
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    GAAPSDSPIV VAPSGAPSPP LSSTGDVASD SYNNVYRDTE GLRELGVTHY
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Kl Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Klotho (KL)
    别名
    alpha-kl Peptide, KL Peptide, LOC100223456 Peptide, klotho Peptide, Klotho Peptide, KL Peptide, Kl Peptide, kl Peptide, LOC100533542 Peptide
    背景
    Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.

    Alias Symbols: alpha-kl

    Protein Size: 1014
    分子量
    116 kDa
    基因ID
    16591
    NCBI登录号
    NM_013823, NP_038851
    UniProt
    O35082
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