Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptide
KIFAP3
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978972
发货至:
中国
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Contact Info
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中国
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Quick Overview for Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptide (ABIN978972)
抗原
KIFAP3
(Kinesin Associated Protein 3 (KIFAP3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-KIFAP3 Antibody(ARP55127_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))
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背景
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The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: APC,KIF3B,KIFAP3,MAP3K10,MINK1,RAP1GDS1,RBFOX1,RPGR,SMC3,SRC,APC,AR,MAP3K10,MAP3K11,RAP1GDS1,SMC3,SRC
Protein Size: 792 -
分子量
- 91 kDa
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基因ID
- 22920
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NCBI登录号
- NM_014970, NP_055785
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UniProt
- Q92845
抗原
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