KH-Type Splicing Regulatory Protein (KHSRP) (Middle Region) Peptide
KHSRP
适用: 人
宿主: 合成
WB, BP, IHC
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- 抗原 See all KHSRP products
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
- 序列
- WEEYYKKQAQ VATGGGPGAP PGSQPDYSAA WAEYYRQQAA YYGQTPGPGG
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-KHSRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- 背景
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KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Alias Symbols: FBP2, FUBP2, KSRP, MGC99676
Protein Size: 711 - 分子量
- 73 kDa
- 基因ID
- 8570
- NCBI登录号
- NM_003685, NP_003676
- UniProt
- Q92945
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