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Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide

KEAP1 适用: 人 宿主: 合成 BP, IHC, WB
产品编号 ABIN978874
发货至: 中国
  • 抗原 See all KEAP1 products
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    宿主
    资源
    • 8
    合成
    应用范围
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-KEAP1 antibody (Catalog #: ARP34727_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    别名
    INrf2 Peptide, KLHL19 Peptide, INRF2 Peptide, mKIAA0132 Peptide, Inrf2 Peptide, fb36f11 Peptide, keap1 Peptide, wu:fb36f11 Peptide, KEAP1 Peptide, klhl19 Peptide, zgc:171654 Peptide, kelch like ECH associated protein 1 Peptide, kelch-like ECH-associated protein 1 Peptide, Kelch-like ECH-associated protein 1 Peptide, kelch-like ECH-associated protein 1a Peptide, kelch like ECH associated protein 1 L homeolog Peptide, kelch-like ECH-associated protein 1b Peptide, KEAP1 Peptide, Keap1 Peptide, keap1a Peptide, keap1 Peptide, keap1.L Peptide, keap1b Peptide
    背景
    KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    Alias Symbols: INrf2, KLHL19

    Protein Interaction Partner: BPTF,ETF1,FAM46A,MYO7A,NFE2L2,ARCN1,BBS1,BTRC,C10orf119,COPG,CUL3,ETF1,FAM123B,FAM129B,GABPA,GBAS,GET4,KIAA0564,MAD2L1,MAZ,MYO7A,NFE2L2,OSBPL10,PFAS,PGAM5,RBM45,SASS6,SLK,SQSTM1,TMEM160,TSC22D4,UBC,USP11,ZRANB1

    Protein Size: 624
    分子量
    70 kDa
    基因ID
    9817
    NCBI登录号
    NM_203500, NP_987096
    UniProt
    Q14145
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