Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide
KEAP1
适用: 人
宿主: 合成
BP, IHC, WB
产品编号 ABIN978874
发货至:
中国
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Contact Info
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Quick Overview for Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide (ABIN978874)
抗原
KEAP1
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-KEAP1 antibody (Catalog #: ARP34727_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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背景
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KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: INrf2, KLHL19
Protein Interaction Partner: BPTF,ETF1,FAM46A,MYO7A,NFE2L2,ARCN1,BBS1,BTRC,C10orf119,COPG,CUL3,ETF1,FAM123B,FAM129B,GABPA,GBAS,GET4,KIAA0564,MAD2L1,MAZ,MYO7A,NFE2L2,OSBPL10,PFAS,PGAM5,RBM45,SASS6,SLK,SQSTM1,TMEM160,TSC22D4,UBC,USP11,ZRANB1
Protein Size: 624 -
分子量
- 70 kDa
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基因ID
- 9817
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NCBI登录号
- NM_203500, NP_987096
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UniProt
- Q14145
抗原
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