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Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptide

KCNN3 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN978826
发货至: 中国
  • 抗原 See all KCNN3 products
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-KCNN3 antibody (Catalog #: ARP35097_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    别名
    KCa2.3 Peptide, SK3 Peptide, SKCA3 Peptide, hSK3 Peptide, potassium calcium-activated channel subfamily N member 3 Peptide, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 Peptide, Kcnn3 Peptide, KCNN3 Peptide
    背景
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

    Alias Symbols: SK3, hSK3, SKCA3, KCa2.3

    Protein Size: 736
    分子量
    81 kDa
    基因ID
    3782
    NCBI登录号
    NM_002249, NP_002240
    UniProt
    Q9UGI6
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