Lysine (K)-Specific Demethylase 6B (Kdm6b) Peptide
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Quick Overview for Lysine (K)-Specific Demethylase 6B (Kdm6b) Peptide (ABIN978704)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-JMJD3 antibody (Catalog #: ARP40102_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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背景
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JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Alias Symbols: KIAA0346, JMJD3
Protein Size: 644 -
分子量
- 70 kDa
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基因ID
- 23135
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NCBI登录号
- NM_001080424
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UniProt
- O15054
抗原
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