Lysine (K)-Specific Demethylase 4C (KDM4C) (Middle Region) Peptide
KDM4C
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978700
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Lysine (K)-Specific Demethylase 4C (KDM4C) (Middle Region) Peptide (ABIN978700)
抗原
KDM4C
(Lysine (K)-Specific Demethylase 4C (KDM4C))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-JMJD2C antibody (Catalog #: ARP32974_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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背景
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JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Alias Symbols: FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1
Protein Size: 1056 -
分子量
- 120 kDa
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基因ID
- 23081
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NCBI登录号
- NM_001146695, NP_001140167
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UniProt
- F5H347
抗原
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