Janus Kinase 3 (JAK3) (Middle Region) Peptide
JAK3
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all JAK3 products
- JAK3 (Janus Kinase 3 (JAK3))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-JAK3 antibody (Catalog #: ARP54306_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- JAK3 (Janus Kinase 3 (JAK3))
- 背景
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JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Protein Interaction Partner: JAK3,JAK3,ALK,CD247,CD40,CXCR4,FES,IL2RB,IL2RG,IL4R,IL7R,INPP5D,IRS1,IRS2,JAK1,JAK2,JAK3,KHDRBS1,LCK,PIK3R1,PRMT5,PTK2B,PTPN2,PTPN6,PTPRC,SH2B2,SHB,SOCS1,SOCS3,STAM,STAM2,STAT3,STAT5A,TIAF1,VIL1,ALK,CD247,CD3E,CXCR4,IL2RG,IRS1,LEPR,PRMT5,PTK2B,SHB,STAM,STAM2,STAT5A,STAT5B,TIAF1
Protein Size: 1124 - 分子量
- 125 kDa
- 基因ID
- 3718
- NCBI登录号
- NM_000215, NP_000206
- UniProt
- P52333
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