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Interferon Regulatory Factor 8 (IRF8) (Middle Region) Peptide

IRF8 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978616
发货至: 中国
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Quick Overview for Interferon Regulatory Factor 8 (IRF8) (Middle Region) Peptide (ABIN978616)

抗原

IRF8 (Interferon Regulatory Factor 8 (IRF8))

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    产品特性

    This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100842_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    IRF8 (Interferon Regulatory Factor 8 (IRF8))

    背景

    Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.

    Alias Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8

    Protein Interaction Partner: COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC

    Protein Size: 426

    分子量

    48 kDa

    基因ID

    3394

    NCBI登录号

    NM_002163, NP_002154

    UniProt

    Q02556
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