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Interferon Regulatory Factor 6 (IRF6) Peptide

IRF6 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978612
发货至: 中国
  • 抗原 See all IRF6 products
    IRF6 (Interferon Regulatory Factor 6 (IRF6))
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-IRF6 antibody (Catalog #: ARP43608_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    IRF6 (Interferon Regulatory Factor 6 (IRF6))
    别名
    IRF6 Peptide, lps Peptide, pit Peptide, pps Peptide, vws Peptide, ofc6 Peptide, xIRF-6 Peptide, DKFZp469E012 Peptide, LPS Peptide, OFC6 Peptide, PIT Peptide, PPS Peptide, PPS1 Peptide, VWS Peptide, VWS1 Peptide, zgc:63500 Peptide, AI876454 Peptide, E230028I05Rik Peptide, mirf6 Peptide, interferon regulatory factor 6 Peptide, interferon regulatory factor 6 S homeolog Peptide, IRF6 Peptide, irf6 Peptide, irf6.S Peptide, Irf6 Peptide
    背景
    IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

    Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1

    Protein Interaction Partner: LBP

    Protein Size: 591
    分子量
    65 kDa
    基因ID
    3664
    NCBI登录号
    NM_004661, NP_006138
    UniProt
    O14896
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