Interferon Regulatory Factor 3 (IRF3) Peptide
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Quick Overview for Interferon Regulatory Factor 3 (IRF3) Peptide (ABIN978600)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IRF3 antibody (Catalog #: ARP31992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IRF3 (Interferon Regulatory Factor 3 (IRF3))
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背景
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IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: CDKL2,CREBBP,CXCL10,E6,IRF3,CREBBP,EP300,GRIP1,IKBKE,IRF3,IRF5,IRF7,MAVS,PIAS4,PPIB,PRDX1,RELA,SERPINB2,SMURF2,SYT1,TBK1,TICAM1,TICAM2,CREBBP,DDX58,IKBKE,IRF5,IRF7,PPIP5K1,PRDX1,TANK,TBK1
Protein Size: 427 -
分子量
- 47 kDa
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基因ID
- 3661
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NCBI登录号
- NM_001571, NP_001562
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UniProt
- Q14653
抗原
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